A Tragedy, Not a Statistic
When my mother was a little girl, her older brother died in a tragic hunting accident.
He was run over by a train.
Now, while that may seem like a non sequitur, it illustrates one of the great tragedies of our day. Namely, that people die, in many and varied and tragic ways. And this happens every day. 204 people die of Alzheimer’s related complications. 196 due to diabetes mellitus. Another 126 die from kidney disease. Drug related deaths take 105 people daily, while alcohol wipes out an additional 64. Fifty die during an assault. All of this pales in comparison to major cardiovascular diseases, which take out another 2200 people. And yes, those are per day.
Grim numbers indeed.
What really pales in comparison to these numbers are deaths from COVID-19. As of this writing, fewer than 2000 people have passed away in the United States due to illnesses related to and complications from the coronavirus. Around the world, the death toll from this is shockingly low, relative to the response. And this is considering, as I do, that the CCP and many other governments are probably under reporting.
During the height of the 2018 flu season, deaths averaged well over 5000 per week. The mortality rate for the 2017 season was 2 deaths per 100,000 people. That was the worst year for flu since 1976. Right now, we are at around 2000 total deaths in the United States for the coronavirus for all of the last two months. And this is from over 100,000 infections. And this mortality rate will drop as further testing comes on line, mostly due to the greater numbers of found cases versus the number of deaths.
Many people will point to the devastation that has happened in Italy over the virus, with over 4,000 deaths out of 47,000 confirmed cases, quickly shooting it past China in the virus’ impact. But there are problems with these numbers:
“The age of our patients in hospitals is substantially older – the median is 67, while in China it was 46,” Prof Ricciardi says. “So essentially the age distribution of our patients is squeezed to an older age and this is substantial in increasing the lethality.” But Prof Ricciardi added that Italy’s death rate may also appear high because of how doctors record fatalities.
“The way in which we code deaths in our country is very generous in the sense that all the people who die in hospitals with the coronavirus are deemed to be dying of the coronavirus. On re-evaluation by the National Institute of Health, only 12 per cent of death certificates have shown a direct causality from coronavirus, while 88 per cent of patients who have died have at least one pre-morbidity – many had two or three,” he says.
This placing of at best semi-related cases into the bucket of COVID virus deaths overinflates peoples perceptions of its dangers, while at the same time lowering the level of factual information about the progress of the disease. Right now, the WHO lists the mortality rate for the disease at 3.4%, a seemingly terrifying number. But with further analysis, that number is questioned:
Projecting the Diamond Princess mortality rate onto the age structure of the U.S. population, the death rate among people infected with Covid-19 would be 0.125%. But since this estimate is based on extremely thin data — there were just seven deaths among the 700 infected passengers and crew — the real death rate could stretch from five times lower (0.025%) to five times higher (0.625%). It is also possible that some of the passengers who were infected might die later, and that tourists may have different frequencies of chronic diseases — a risk factor for worse outcomes with SARS-CoV-2 infection — than the general population. Adding these extra sources of uncertainty, reasonable estimates for the case fatality ratio in the general U.S. population vary from 0.05% to 1%.
As we test more and more people, the numbers of asymptomatic carriers will increase, along with mild cases. I have a strong suspicion that the numbers for the deaths recorded around the world are equally bad, inflated due to other concerns of professionals at best tangentially related to the matter at hand. At the same time, we need to recognize that the average age of mortality due to the coronavirus is spread between people in their fifties and nineties, and the vast majority of these cases are people with multiple complications. This is the type of information we need to help manage the risk of COVID-19 and not panic.
We, along with most of the Western world, are shutting our doors, stalling our economies over what is essentially a drop in the bucket of deaths. And with this shuttering will come side effects and reverberations for a very long time. As opposed to letting people manage their own risk levels, we have collectively decided to stop the world. Two weeks we are told, but to what end? This will not bring about a cure, the development of which is surely months, if not years away. But in the meantime, we huddle inside our homes, regardless of the number of cases in our state or city.
Right now, we are starting to have a good set of test regimens come online, which will in turn increase our knowledge of the disease and its transmission rates. And as we do this increased testing, we can compare the rates of people who don’t have the disease at that current time, the people who have the disease but no effects, those who have mild effects and those with debilitating effects. We already have an idea of the numbers hospitalized and that have died from it (assuming we don’t have a coding issue like Italy does). And as these numbers come online, we are seeing that the damage done by the virus is less than initial modeling thought.
Dr. Deborah Birx: (I assume her comments regarding DNR’s is in response to Glen Beck and The Washington Post article)
Models are models. We are — there is enough data of the real experience with the coronavirus on the ground to really make these predictions much more sound. So when people start talking about 20% of a population getting infected, it’s very scary, but we don’t have data that matches that based on our experience.
And the situation about ventilators. We are reassured in meeting with our colleagues in New York that there are still I.C.U. beds remaining and still significant — over 1,000 or 2,000 ventilators that have not been utilized.
Please for the reassurance of people around the world, to wake up this morning and look at people talking about creating DNR situations, Do Not Resuscitate situations for patients, there is no situation in the United States right now that warrants that kind of discussion. You can be thinking about it in the hospital. Certainly, hospitals talk about this on a daily basis, but to say that to the American people and make the implication that when they need a hospital bed it’s not going to be there or a ventilator, it’s not going to be there, we don’t have evidence of that.
I think people know this, and know it quite well, as we see by their reactions and deeds. Yes, some people might be doing foolish things, but in the end they are reacting to and from the information they receive. I spoke this morning to a acquaintance in New Jersey and he was rightly worried about this, and at the same time, many of the people I see in semi-rural Oregon are acting as if little has changed. We are all, in the end, managing our risk. And much like driving a car, we learn of the risks and will still engage in the activity (over 100 deaths per day).
Nothing I present here should stop a person from taking all the precautions that they feel are necessary for themselves or their loved ones. Knowing if one is at risk, either from age or medical complications, should in all cases be used to plan one’s life. I suffer from Multiple Sclerosis. To deal with that disease, to halt its progression through my nervous system, I take an immunosuppressant drug, a glatiramer acetate solution injected three times per week. This makes me susceptible to various infections, and places me at a higher risk for the coronavirus. Indeed, so high I cannot give blood, not due to me spreading a disease, but rather that an infection could be so bad for my health. So, believe me when I say that I am taking the issue very seriously, but at the same time evaluating the risks. And in the end, I refuse to be a bubble boy, trapped in my life by outside factors. On the other hand, my father is in the end stages of Alzheimer’s along with having stage 4 kidney disease. COVID-19 would kill him. Just as the common flu would.
There will be, no matter our precautions, people who will die from this virus. Some will be old and already in teetering condition. Others will be young and seemingly full of life, about to have history unfold for them. And they will still die. Just as surely as a (statistical) child will die in a swimming pool.
Every person who dies from this, or any other cause, is a life to be celebrated, remembered, and mourned. Each and every person is loved by others, remembered by family and friends, and cared for by someone. The damage from their loss of life is incalculable to those who care. By all accounts, the death of my uncle was devastating to my grandmother. Toby was nineteen years old, a pre-med student at UC Berkeley. It broke her in half emotionally to have her son taken away before his time.
The testing is key, and we have not been doing nearly enough of it.Report
I want to acknowledge that this is hard on us. It’s hard to stay at home. It’s hard to tell others to do it. It’s hard to see your beloved comic book store close its doors with the thought it might not come back. It’s hard to see your favorite restaurant, the one you have been going to twice a week for the past 5 years close. This is just hard.
And, I have an issue with the framing of “only X people have died”. The problem is that you didn’t include the word “yet”. We’re still in the leading edge of this thing. On our trendline, we will have reached a million deaths by April 26 (https://www.motherjones.com/kevin-drum/2020/03/coronavirus-growth-in-western-countries-march-27-update/).
Yes, that’s math. I’ve seen remarks, though not from y’all, of “that’s just math, that’s not real”. It makes me shudder. Math put men on the moon.
On this trendline, we will get to a million deaths in three weeks time. That’s how fast this is growing. At a million deaths there might be maybe 3, maybe 5 million serious cases, requiring a ventilator? So a couple thousand unused will be used up.
Predicting this course is not as reliable as calculating trajectories of rockets, but it’s pretty solid. The main thing that will knock us off this trajectory is our own interventions.
We are finishing up our second week of sheltering in place in our county. I’m unsure how long this will continue. I’m quite clear that it is helping a lot. Santa Clara was mentioned as a hot spot three weeks ago. I am willing to do this, because not only does it keep me and my family (my daughter has MS!) safe, it keeps me from being the guy who spreads the virus to 100 other people at a corporate meeting, not knowing I’m even sick. (That happened!)Report
The problem as I see it is trendlines and a lot of the models predicting those trendlines are (relatively) simple linear models, with lots of baked in worst case assumptions.
This is why the testing is so damn important, because it helps eliminate those assumptions and improves the modeling.Report
I (stupidly) got into a fight with a local guy who posts feverishly on FaceBook as an “expert”. He has two speeds: “The numbers are bad and can only get worse” or “The numbers are not-so-bad which means they must get worse.” He claims to have a stats background (maybe he does) but he never offers any actual numbers or analysis. For whatever reason, he is committed to the worst case scenarios and will just force the data to support them. He’ll say something like, “Assume 50% population infection,” and when I challenge that assumption, he just insists we have to assume something. This is a stats guy?! Sure, certain assumptions need to be made, but there are ways of coming up with those assumptions and the ability to run models multiple times and multiple ways with different assumptions to get a range of outcomes. Not for this guy: bad and getting worse or not-so-bad and getting much worse. Only possible routes.
I shared elsewhere. My ex has it. Confirmed diagnosis. (She is doing well and likely will be out of the woods entirely in the next two days). My sons were with her during her contagion period. They then came to me and have been with me for two weeks. None of us show any symptoms, so we can’t get tested. My girlfriend and her daughter were with us for much of the two weeks. Same thing: no symptoms and, therefore, no test.
Right now, this all gets thrown into the data as 1 confirmed case that did not require medical intervention). But it is possibly as many as 6 cases, 5 of them asymptomatic. Or it is 1 case with zero transmission despite intense interaction between parties. Or it is somewhere in between and a mix of both. We just don’t know because the testing isn’t available to us.Report
Testing is the key. Without that we’re just speculating about all the key numbers: infection rate, transmission rate, mortality rate, etc.Report
Though we know that Trump’s TV ratings are extremely high, so there’s that.Report
There is a chance that you are an asymptomatic carrier. I hope not, but this is something that happens.
If we had the testing resources, you would be tested, and if you were a carrier, you would be isolated.
Having said that, I don’t necessarily disagree with the triage decision to not test you.
Yeah, we need more testing. A lot more testing.
And here’s hoping that you and yours stay well!Report
We were already pretty tightly quarantined (only leaving for outdoor exercise and groceries) and have tightened further (no groceries… leaving property only half as often for exercise) due to possibility of asymptomatic carrying. We are cleared on Tuesday.Report
Top line, I endorse this wholly. We need to be doing a lot more testing. We need to get to a ‘test and trace’ scenario. We are slowly getting there, but we aren’t there yet. So what do we do until we get there?
There is a lot we don’t know, I accept that. And there are plausible scenarios where things get very, very bad. They might or might not be correct, but I’m certainly not willing to assume they aren’t the case. That’s terrible risk management.
At the same time, of course the disease will spread during the initial phases following an exponential growth path. How could it do differently? All the data we have says it is doing so.
It might not be so bad, but then it might. We might see 3 million deaths, or it might be 300,000. A lot depends, a lot, on what we do. I am willing to do my thing to keep all y’all and myself safe. We’ll sort out the money stuff. We can figure that out, if we’re still here.Report
I think I disagree with the OP, for many of the reasons Dr. Jay said. I will confess, though, that there’s a lot I don’t really know. People who have a better grasp of the necessary skills (statistics, public health measurements, etc.) can speak to how much the OP is right and how much it is wrong. It’s likely not entirely wrong or entirely right.
This OP implies (maybe not intentionally?) that our current efforts, such as they are, are an overreaction. I certainly hope so!
One final note: if I read the OP right (and please correct me if I”m wrong), it seems to suggest the number of deaths in Italy ascribed to covid19 is inflated. My question, though, is, is the number of deaths in Italy abnormal? Is this just the comparable number of deaths we’d expect any time in Italy? Are tales of bed-shortages and ventilator shortages in Italy exaggerated or nothing unusual? It seems to me the answers to those questions are yes, no, and no. If I’m right about those answers, then a robust response to the covid19 pandemic seems called for.
Again, I hope you’re more right and I’m more wrong. But it doesn’t seem that way.Report
One more thing to add. While you’re going to get A LOT of pushback on this post (my comment being part of that), I do realize this is a time of uncertainty and we’re trying to figure out basic things about what is going on. It’s a fog of war type of situation. We’re all groping for answers. I don’t fault Aaron for advancing his argument, even though I disagree with him quite strongly.Report
Prelim info/study suggesting that Covid death toll may be higher then understood. Very plausible but needs more study there and here.Report
If he’s right then we need good explanations for multiple numbers. The increase in cases is because we’re testing more. The death rate is because we’re putting things into that bucket which shouldn’t be.
If Aaron is right then we WON’T see a sharp increase in the death rate soon which could have been avoided by vents.
And Trump will turn the economy back on for Easter.
If he’s wrong then New York is going to have a nasty few weeks with morgues over flowing, with the rest of the country duplicating that experience aftwards.Report
That’s a heck of an experiment to be running.Report
Yes… but experiment is the right word. Predictions that we can check is the backbone of science.Report
I’d be somewhat less concerned if my job didn’t give me a window into the healthcare system and delivery specifically. Our infrastructure in a lot of places is stretched and under a lot of pressure in the best of times. We aren’t exactly going into this with our best foot forward. A shock that’s manageable in theory could wreak a lot of havoc in practice, and that’s not even getting into the way benefits of all kinds are still overly tied to employment.Report
Correct me if I’m wrong, but wasn’t there a study (warning: large PDF) done in Britain to test the do nothing theory? Indeed, there was. The conclusion of the study was this:
In short, to quote a darling of the right, “facts don’t care about your feelings.”Report
not accounting for the potential negative effects of health systems being overwhelmed on mortality.
That’s the kicker, seems to me. I haven’t seen hard data on this but it seems pretty apparent that death rates are primarily a function of hospital capacity. So they’ve left out a *very* significant factor in their analysis.Report
I’d expect the tussle over resources to get severely nasty. High density economically and culturally important areas would be demanding special attention while rotting hospitals across the deep south and rust belt could end up looking like 3rd world disaster zones. These places were already going bankrupt left and right before this started.Report
I think you’re misreading this. I think the authors are saying the large death toll would happen with an optimally functioning health system.Report
I don’t think so?
They’re saying the unmitigated spread of covid would result in massive loss of life *with* a fully functioning healthcare system, and that their model doesn’t include increased mortality projections due to healthcare system failures. IOW, the death rate in practice would be worse than their model predicts.Report
That’s what I read. I must have misunderstood your original comment.Report
https://www.newscientist.com/article/2238578-uk-has-enough-intensive-care-units-for-coronavirus-expert-predicts/#ixzz6HojQa700
Niel Fergusson is the first name on the paper you link to, and he has walked back the clames of 500k when questioned in front of parament. To be fair, he has waffled back and forth a bit in the time since testifying, which kinda puts him as a less that reliable source. At least in my book.Report
One reason why the stay at home order will fail…
https://www.wthr.com/article/howard-county-bans-sale-books-toys-other-nonessential-itemsReport
Thank you for putting forward a reasonable, empirical perspective that is much lacking in the conversation these days.Report