Thursday Throughput: Leaving on a Superluminal Jet Edition

Michael Siegel

Michael Siegel is an astronomer living in Pennsylvania. He blogs at his own site, and has written a novel.

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95 Responses

  1. Jabberwocky says:

    Opposition to dengue vaccine?
    https://www.npr.org/sections/goatsandsoda/2019/05/03/719037789/botched-vaccine-launch-has-deadly-repercussions

    Apparently Americans are significantly less compliant, in general, than Malaysians.Report

  2. Jabberwocky says:

    https://www.cdc.gov/library/covid19/pdf/2020-09_08-Science-Update_FINAL_public-v2.pdf
    Repeating advice to stay out of elevators.
    Staying outdoors and avoiding close contact with people you don’t live with, is also good.

    You are not superman, do not act like wearing a mask will make you Superman.

    Also: Shouldn’t you be a little worried about how much you know, when the CDC isn’t even publicizing “How Covid19 Spreads”?

    There’s substantial evidence of spreading via a fecal-airborne route. “Do not touch” toilets are a known vector that spread fecal matter into the air, much worse than old-school toilets.Report

    • Jabberwocky in reply to Jabberwocky says:

      Rather difficult to “wear a mask to protect others” if your contamination is coming out your ass, isn’t it?
      I’ll repeat, go look at the date above. That’s September of last year.
      CDC’s had plenty of time to explain to you why masks are not going to work as advertised.
      (Your airflow “through” a mask is through the holes along the sides of it, assuming you aren’t wearing a properly fitted n95 mask).Report

  3. Jabberwocky says:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862259/
    Masks lead to riskier behaviors, although I could just cite the above OP.
    Stay away from others, six feet at a minimum.
    Stay outdoors if you must expose yourself to someone else.
    Get plenty of sunshine.Report

    • CJColucci in reply to Jabberwocky says:

      Seat belts lead to riskier driving.Report

      • Jabberwocky in reply to CJColucci says:

        https://www.jstor.org/stable/42956203
        Facts not proven.

        People who are generally risk adverse stop perceived “risky behaviors”, and those tend to cluster.

        What’s idiotic is that perceived “risk adverse” people think that “going to the grocery store” is not a high risk activity, despite having been told that by the CDC.

        Going indoors with others is a high risk activity (using a public restroom is an EXTREMELY high risk activity).
        Do not do it simply because you have a (probably ineffective) mask.

        Do not do it simply because you’re a boomer and can’t imagine death killing you at a grocery store.

        I’m pretty sure that I’m the only one who still washes hands for 2 minutes after touching the mail, or handling my front door (that some jerk might have licked).

        Y’all are walking disease vectors, and I’m stayin’ the hell away from you.Report

        • Dark Matter in reply to Jabberwocky says:

          Lazy man’s solution is to buy a better mask. Brick of 10 N95s was something like $18 on Amazon.Report

          • Jabberwocky in reply to Dark Matter says:

            Lazy is exactly right.
            Properly fitted n95 masks are what’s needed, if you want them to be effective.

            “Surgical masks are designed to provide barrier protection against droplets, however they are not regulated for particulate filtration efficiency and they do not form an adequate seal to the wearer’s face to be relied upon for respiratory protection. Without an adequate seal, air and small particles leak around the edges of the respirator and into the wearer’s breathing zone.”
            https://blogs.cdc.gov/niosh-science-blog/2020/03/16/n95-preparedness/

            We know this is an airborne virus. That means that surgical masks are ineffective. If you are not creating/ingesting droplets, wearing a surgical mask isn’t gonna do much.Report

            • Philip H in reply to Jabberwocky says:

              “proper fit” isn’t actually hard with N95s unless you have facial hair. Then you won’t get a good seal no matter what.Report

              • Jabberwocky in reply to Philip H says:

                Instructions at link.Report

              • Philip H in reply to Jabberwocky says:

                I spent the first half of may career as a lab scientists, fitted annually for far more complicated respirators. And every time I was told my facial hair would – except in negative pressure settings – keep me from a perfect seal. There’s nothing there that dissuades me from that understanding.Report

              • Jabberwocky in reply to Philip H says:

                Wasn’t disagreeing.
                Simply providing information.
                Haven’t ever been fitted for an N-95, but I do hear that facial hair is a bugaboo.
                (And, yes, an N-95 is a relatively porous respirator.
                I have clean-room grade air filters at home —
                not the high end kind, the $1000 buck kind.
                Run them at high, and they will /probably/ clear the room of original COVID-19 before you catch it.)Report

              • Dark Matter in reply to Philip H says:

                You’re not wrong, but that just means we’ll have to shave.

                Now it’d be nice if the powers that be were suggesting that, and for that matter it’s weird that we don’t have the medical authorities suggesting N95s.Report

              • Facial hair was forbidden at the refinery I used to work with for just that reason. In case of emergency (fires, leaks, etc.), they needed to wear an air-pack with a tightly-sealed mask.Report

              • Oscar Gordon in reply to Mike Schilling says:

                Big part of the justification for it in the Navy, especially in engineering spaces. Fighting a fire in a ship means everyone is wearing respirators.Report

              • JS in reply to Mike Schilling says:

                First thing my father did when he retired was grow a goatee.

                Same reason — he needed to get a good seal with emergency equipment because he worked at a refinery.

                he’s had it ever since, so I guess he likes the look.

                That being said, he did manage a mustache for a number of years anyways, but apparently that allowed for a seal, although there were some rigorous rules on length and whatnot and regular testing to ensure he could get a seal.Report

        • CJColucci in reply to Jabberwocky says:

          So we’re both wrong?Report

      • Chris in reply to CJColucci says:

        The compensating behavior theory has been, at least for seat belt usage, pretty thoroughly falsified, has it not?Report

    • Chip Daniels in reply to Jabberwocky says:

      Stay outdoors if you must expose yourself to someone else.

      Someone owes me a new keyboard.Report

  4. Jabberwocky says:

    https://medicalxpress.com/news/2021-08-vaccine-tuberculosis-older-people-covid-.html
    “Have you had your mandatory vaccination yet?”
    “I got TB vaccinated.”
    (Yes, I realize there’s different supply chains for the two vaccines — but if they’re ameliorating the “old/fat/diabetic” die of this, why not consider it?)Report

  5. Jaybird says:

    ThTh8: This is exceptionally frustrating. I know that expecting 100% from a vaccine is not *ENTIRELY* rational (though, golly, the polio and smallpox thing worked well, didn’t it?) and having a vaccine that protects a mere 80% instead of 95% shouldn’t get someone to say “the vaccine doesn’t work!”

    It does work. It’s just not, you know, perfect.

    But echoes of pre-vaccine talking points keep showing up and that’s disheartening.Report

    • Oscar Gordon in reply to Jaybird says:

      The thing to keep in mind is that with Polio & Smallpox, there was a worldwide, practically heroic effort to wipe those diseases out, and each one still took decades to do.

      https://scibabe.com/daily-mos-the-eradication-of-smallpox-part-i/
      https://scibabe.com/daily-mos-the-eradication-of-smallpox-part-ii/Report

      • Jabberwocky in reply to Oscar Gordon says:

        During which we withdrew multiple vaccines, due to safety concerns.
        (I approve of vaccines. They’re a clever use of our own immune system. That is not to say they come without risks, or to say that this particular “non-sterilizing” vaccine should not be responsibly evaluated).

        The FDA’s own EUA talks about Antibody Dependent Enhancement (and how it was not tested for during the studies that greenlit the EUA). We cannot accurately tell if it is occurring without solid reporting — and when someone within 10 days of being double-jabbed is reported as “Died of COVID-19” — and hence not reported as a ADE vaccine casualty, it concerns me.

        This may be an indication that our data is being improperly reported, because of improper training in “What Could be a Side Effect of the Vaccine?”Report

        • Philip H in reply to Jabberwocky says:

          Considering that you have medical examiners in Missouri on the record as not listing COVID as a cause of death to make loved ones feel better, I’d say there’s a lot of improper reporting going around.Report

    • Jabberwocky in reply to Jaybird says:

      https://www.icelandreview.com/ask-ir/whats-the-status-of-covid-19-in-iceland
      (More vaccinated people than unvaccinated people catching the virus. — this is at American levels of vaccination. 60% total, 70% one jab.)
      Israel is publishing a 39% efficacy of Pfizer’s vaccine.Report

    • Dark Matter in reply to Jaybird says:

      The original covid vaccine worked as well as the small-pox or polio vaccines against the original covid virus.

      That’s for 2 shots of polio, take that to three shots and it goes to 99%… but that might be true for Covid’s too.

      In theory the US could go to three shots and presumably that would help. Save some American lives although the bulk of the current problem is the people who have zero shots.

      It would be stupid-selfish for us to do that since the world has only about 15% of the population vaccinated.Report

      • Jabberwocky in reply to Dark Matter says:

        You are being incredibly inaccurate.
        Please come prepared to talk about the differences between a sterilizing and a non-sterilizing polio vaccine, and why the later was withdrawn as soon as we had the former.

        I am unsure where this idea that we have a “current problem” comes from.
        We have people dying, sure, but we always have people dying.
        A “problem state” is where we have more people dying because our medical system cannot handle the number of people.

        Considering that we are actively giving monoclonal antibodies to the vaccinated as a COVID-19 treatment, what does that tell you about our current level of antibody matching?Report

        • Philip H in reply to Jabberwocky says:

          What percentage of COVID patients are getting monoclonal treatment? because last I heard its considered too expensive for the masses.

          That aside, we as a nation are now over 600K EXCESS deaths due to COVID. we also – for a third time in the pandemic – have hospitals reliably reports capacity and staffing strains due to COVID. Most Americans – the ones with their heads not firmly in Trump’s backside – interpret that as a problem state.Report

          • Jabberwocky in reply to Philip H says:

            I’m not going to give you confidential information.
            Seems more likely from what I read, that it’s still in “research” stages, and that means “research hospitals are enrolling patients as fast as they can.” (again, this is not confidential information).

            Yes? 4 times a bad influenza year. That’s not bad for a novel virus.
            “Capacity and staffing strains” are not what I’m hearing locally.

            And I want to hear “We are letting Grandma Die because we can’t afford the ventilator” before I am saying “Okay, we got a big problem.”
            (Low key, this was happening in Italy. That was a Bad Time.)

            I will also accept “Doctors are ringing other states to learn how to use a ventilator, because All The Nurses Are Gone” (what, you thought a doctor could do manual labor?)

            Hospitals who fire half their nurses and want cheaper ones can complain about staffing strains. This doesn’t mean it’s caused by covid19 and not dumb bean counters.Report

            • Philip H in reply to Jabberwocky says:

              the bigger of the three hospitals in Baton Rouge now has a Public Health Service Disaster Medical Assistance Team on board for 30 days to augment staff resources for treating COVID. Again most people look at that as a BIG PROBLEM.

              As to the monoclonal treatments – you may not want to give out “confidential” information, but NBC has good reporting:

              The Food and Drug Administration’s action on Friday brings hope to the estimated 3 percent of Americans who are immunocompromised, including those with autoimmune diseases, HIV patients, cancer patients and organ transplant recipients, who may still be vulnerable to Covid even after being fully vaccinated.

              This is the first time an injectable coronavirus antibody treatment has been approved for use as a prevention of Covid after someone has been exposed to the virus.

              https://www.nbcnews.com/health/health-news/fda-authorizes-covid-antibody-treatment-preventive-after-exposure-n1275737

              However, the FDA said in its statement issuing the emergency expanded authorization that monoclonal antibodies should not be considered a vaccination substitute. The agency urged all who are eligible to get vaccinated.

              “It’s good to know that for people who do not respond well to vaccines, including those who do not make antibodies, we can now help protect them against getting infected with SARS-CoV-2 by giving them antibodies following exposure,” said Dr. Ghady Haidar, a transplant infectious diseases physician at the University of Pittsburgh Medical Center.

              Report

              • Dark Matter in reply to Philip H says:

                So if you have AIDS or an organ transplant and effectively don’t have an immune system, you can take “monoclonal antibodies” and that might help.

                Everyone else should depend on the vaccine. For that matter even people with seriously damaged immune systems should take the vaccine even if they’re going to take monoclonal antibodies if they’re exposed.Report

              • Philip H in reply to Dark Matter says:

                That’s how I read it. It doesn’t read as a general treatment.Report

              • Jabberwocky in reply to Dark Matter says:

                Or if you’re morbidly obese.
                “compromised immune system” goes with diabetes and being very very fat.
                That’s why the under 18 who die of covid19 aren’t ever pictured in the papers.Report

              • Dark Matter in reply to Jabberwocky says:

                Yeah, I assume a lot of the people under the age of 18 have something pretty seriously wrong. Diabetes, cancer, organ trans, aids, something else.

                Having said that, it could also just be got REALLY unlucky. Initial exposure was to a family member for a very long time and they got slapped with an extremely large initial dose of the virus.

                Even if you’re young, not getting vacinated is taking a stupid risk. It’s a negative lottery, you can’t “win(lose)” if you don’t play.Report

              • Jabberwocky in reply to Dark Matter says:

                If your ACE2 receptors don’t accept spike proteins, you aren’t going to get viral replication.
                That said, you can still have your entire immune system run amok, theoretically, if you are inundated with viral load (of course, the same can be said for being inundated with spike protein).Report

              • Jabberwocky in reply to Philip H says:

                You’re citing monoclonal antibodies for prophylactic use.
                My reporting was on using monoclonal antibodies for outpatient therapy after diagnosis of COVID19 (older reporting had use of them inpatient, but I didn’t catch them mentioning the vaccinated).

                https://inside.upmc.com/two-pittsburghers-receive-sotrovimab/?_ga=2.164115903.1252836163.1628191007-310173421.1569352438

                Unlike for prophylactic use, this is not being given only to those with severe medical conditions, seemingly (at least the article doesn’t say so).Report

              • Jabberwocky in reply to Philip H says:

                “Public Health Service Disaster Medical Assistance Team” sounds fascinating.
                What level of governance is that from?
                When did it get started?
                Why didn’t NYC get one of those?

                Is Baton Rouge’s hospital a solo operation? I know larger outfits were able to shift nurses around during crunch times…Report

              • Philip H in reply to Jabberwocky says:

                https://www.phe.gov/Preparedness/responders/ndms/ndms-teams/Pages/dmat.aspx

                DMATs are a federal level response. There are also in Texas at the moment – https://www.newsweek.com/federal-disaster-medical-teams-deployed-texas-coronavirus-cases-surge-1516892

                No idea if NYC has had any . . .

                There are three separate hospitals in BTR – two are independent and one is part of a larger system in south Louisiana and Mississippi.Report

              • Jabberwocky in reply to Philip H says:

                Earlier reporting from Scientific American:
                https://www.scientificamerican.com/article/why-monoclonal-antibody-covid-therapies-have-not-lived-up-to-expectations/

                Monoclonal antibodies have been greenlit as a TREATMENT for a while, now.Report

              • Philip H in reply to Jabberwocky says:

                They had the same EUA the vaccines now have, until the final authorization I noted above. That article also notes the use case approved by the FDA was restricted as was the potential targets. And the article notes that:

                Currently the NIH COVID treatment guidelines recommend that one of the two cocktails be administered for the treatment of outpatients diagnosed with mild to moderate COVID infection who are at high risk of progression to severe disease. The treatment criteria include having a body mass index of 35 or more, being 65 or older, having diabetes, chronic kidney disease or an immunosuppressive disease, or taking an immunosuppressive drug. Some people younger than 65 are also eligible if they meet specific requirements. Data on the use of these drugs for patients younger than 18 years old are limited.

                Which, like the full approval article I linked to, means that this is not a “get out of jail free card” from most unvaccinated people, and that it’s not likely to be used for vaccinated people since so few of them get to moderate cases likely to progress to severe cases. It also nots that overwhelmed hospitals have problems administering the drug cocktail.

                And none of that points to widespread use, much less widespread applicability. We MAY get there, but until then the non-sterilizing vaccine you don’t like and the mask you want us to ignore are still a better bet for the general population.Report

            • JS in reply to Jabberwocky says:

              “I’m not going to give you confidential information.”

              Translation: “I am lying and fabricating the reality I wish existed. Please do not call me on this”Report

        • Dark Matter in reply to Jabberwocky says:

          You are being incredibly inaccurate.

          The original Covid-vac had a 95% effective rate.
          A ten second google search for polio and small-pox end up with similar rates (although with polio we have the 2 shots vs 3 shots thing).

          Please come prepared to talk about the differences between a sterilizing and a non-sterilizing polio vaccine, and why the later was withdrawn as soon as we had the former.

          It’s been enough decades that I assume it’s a resolved matter. If you want to claim the original polio vaccine wasn’t the best I won’t argue the point.

          It does seem like you’re trying to bury me in details when I’m taking a 10,000 foot level appoach.

          I am unsure where this idea that we have a “current problem” comes from.

          Part of it is I’m moving to a Florida hot spot which is making the news on the hospitals being slammed and their covid graphs are going past their previous highs.

          Another part is it’s looking like the vaccines are less good against Delta (less good isn’t the same as “not very useful”).

          Considering that we are actively giving monoclonal antibodies to the vaccinated as a COVID-19 treatment, what does that tell you about our current level of antibody matching?

          I suspect the that number of people getting “monoclonal antibodies” rounds to zero and that we’re trying all sorts of stuff to see if it works and how well. Right after that the mainstream media turns it into click bait.Report

          • Jabberwocky in reply to Dark Matter says:

            Can I just cite the polio vaccine when I make the case that this COVID-19 vaccine (all of the non-sterilizing ones) ought to be withdrawn, and that we ought to go with a sterilizing vaccine instead? (We did withdraw the Salk vaccine because it was non-sterilizing).

            Non-sterilizing vaccines have a horrible track record, and shouldn’t be given to everyone, as they turn everyone into breeding pits for worse diseases.

            They could, with some amount of care, have been given to the people at most risk for this disease. As those are the elderly and extremely fat, we’d have run a much smaller risk of a Thalidomide situation.Report

            • Dark Matter in reply to Jabberwocky says:

              Can I just cite the polio vaccine when I make the case that this COVID-19 vaccine (all of the non-sterilising ones) ought to be withdrawn,

              Only if you can show that the current vaccines were proven to work only with 1930’s standards. A trial of a few dozen people, and ignoring serious experts in the field deeply concerned by it at the time.

              I hadn’t heard about this “non-sterilising vs sterilising” issue before but with a few minutes of looking into it I found sterilising is the ideal, and hard, and rare. I’d post a quote saying most vaccines are non-sterilising but this is the wrong computer.

              Mass media says Pfizer’s vac will be fully approved by the FDA in a month.Report

            • PD Shaw in reply to Jabberwocky says:

              The polio vaccine is not a sterilizing vaccine. Everybody that gets the vaccine gets infected, nobody gets polio.

              The Salk vaccine was not withdrawn because it was non-sterilizing, but because of an error in manufacturing a batch that caused live virus to be given to children, giving some polio. Something impossible with an MRNA vaccine.

              You are peddling nonsense.Report

              • JS in reply to PD Shaw says:

                The phrase “non-sterilizing vaccine” as well as his previous contention about “it’s a blood infection not a respiratory one” didn’t clue you in? (As noted, quite a few common vaccinations aren’t sterilizing. But he doesn’t seem to grasp that. Or he thinks the difference is vitally important to COVID for some word salad reason)

                He’s basically cherry picking sciency sounding phrases from various articles dating back to the very beginning of this plague and forcing them to fit into whatever he wants reality to be.

                It’s sovereign citizening of virology.

                No more sense arguing with him than arguing the law with a man screaming about gold fringed flags.Report

          • PD Shaw in reply to Dark Matter says:

            Kids still get polio vaccines. It is a four dose regiment:

            ·A dose at 2 months
            ·A dose at 4 months
            ·A dose at 6-18 months
            ·A booster dose at 4-6 years

            I was just talking about this with my family yesterday because I was sharing a memory of going to the doctor when I was btw/ 11-15 and getting my vaccination record certified. It turned out that I had not gotten the last dose of the polio vaccine. At this point, it might be important to know my dad got polio a couple of years before the vaccine was publicly available. I remember looking at my mom to see if she would say anything, and she told the doctor that she did not know if it mattered, but my dad had polio. The doctor said it was not hereditary, wrote something on the paper and gave it back to her.

            I’ve always wondered what he signed, but my mom didn’t remember any of it.Report

            • Dark Matter in reply to PD Shaw says:

              So if we go to 4 shots, we might get something that gives full immunity to Covid?Report

              • Dark Matter in reply to Dark Matter says:

                Who said every few weeks? Polio is 4 total. Every 6 months is fine, maybe even retooling it to target the “new” varients.

                In the meantime, you’re at “get a shot every 6 months” at $20+ a pop for Pfizer.

                $40 * 330 million people is $1.3 Billion.

                In the context of a pandemic, that’s free.

                The gov will pay for it because the amount of economic destruction if it doesn’t is VASTLY greater.

                Not only can we do that one year but we can do that every year.Report

              • Dark Matter in reply to Dark Matter says:

                Dropped a zero. It’s $13 Billion.

                Still Free.Report

              • PD Shaw in reply to Dark Matter says:

                I believe the polio vaccines have a neutralizing antibody response (blocks some virus from infecting cells and replicating), but the main impact is that memory B and T cells prevent infected cells from causing disease. Is that “full immunity”? I think the main point is that a vaccine can be very effective even if does not completely block infections before they occur.Report

              • Dark Matter in reply to PD Shaw says:

                In the news: Report: FDA to Unveil Booster Dose Strategy by Early September

                As Jabberwocky and others have pointed out, the vaccine is struggling against some variants and/or in some populations.

                The FDA (and other medical powers that be) seems to be leaning towards a third shot. I assume the gov will continue to pay for it because Economics and Politics.

                And yes, the poor world which has been squeaking about “equity” will no doubt squeak harder about it since the First World would be “diverting” something like a Billion doses back towards our use.

                On a side note, yes, I fully expect if we need a 4th shot then that’s what will happen. Ditto a 5th, etc. We’re years away from fixing this and vaccination continues to be the big magic bullet.

                https://gizmodo.com/report-fda-to-unveil-booster-dose-strategy-by-early-se-1847436397/ampReport

              • PD Shaw in reply to Dark Matter says:

                I am a Delta denialist. My alphabet goes right to epsilon, it’s more efficient that way.

                I think the FDA is hearing from doctors who want to give a third dose to certain immunocompromised individuals. The vaccine is still effective for this group (lowest CDC reports is 59% effective against COVID-19 hospitalization), but not as high as those without immune compromise (91% in the same study).

                But don’t assume that these various studies are very rigorous in terms of analyzing all of the different ways our body’s immune systems protect us from viruses. The easiest studies appear to be measuring antibodies following infection/vaccination, but antibodies are supposed to decline. The immune system has a lot of pathogens to take care of. The memory cells are for longer term. Do studies you look at try to measure them?Report

              • Michael Cain in reply to PD Shaw says:

                I think the FDA is hearing from doctors who want to give a third dose to certain immunocompromised individuals.

                As I understand the rules — which is quite possibly entirely wrong — as soon as the vaccine is fully licensed, doctors can recommend off-label uses, which would include a third dose. They can’t legally recommend off-label uses under an EUA.Report

              • PD Shaw in reply to Michael Cain says:

                I’m not sure of the rules either but Alex Tabarrok recently implied that the EUA allowed changes to be made that might include a boost. He quotes an HHS official about what can happen within the EUA process: “You can change the labeling. You can change the information. You can change the dosage. You can give it to populations for which [it] wasn’t approved.”

                https://marginalrevolution.com/marginalrevolution/2021/08/the-most-important-act-of-the-last-two-decades.html#comments

                That certainly doesn’t sound like it allows off-label uses, but some regulatory action would need to take place for third doses that hasn’t taken place.Report

              • Jaybird in reply to Michael Cain says:

                Colorado is a state that has legislation (theoretically) forbidding the requiring of ID for the vaccination.

                I have been tempted by the thought of a 3rd dose of Moderna.Report

  6. [ThTh2] Should we switch to ASCAP?Report

  7. Jabberwocky says:

    Nightmare Scenario from Original Covid-19 was more than just 20million dead.
    That was 20million dead, first wave.
    https://www.cell.com/cell/fulltext/S0092-8674(20)30610-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867420306103%3Fshowall%3Dtrue
    Substantial reason to think that we might not be able to get a good, long-lasting adaptive immune response.

    Now, the available vaccines may put us into a different nightmare scenario… but that’s the one where we’re ruled, officially and in public, by China.Report

  8. Jaybird says:

    Nate Silver has an interesting thread here. I don’t know about his percentages but his categories seem about right to me.

    (I’m group B.)

    Report

    • Philip H in reply to Jaybird says:

      Most days I’m group B. when my introverted side is overloaded, I slide into group A.Report

    • PD Shaw in reply to Jaybird says:

      I don’t belong in any group.

      I am not worried about Delta or any scarients, so that suggests C, but I don’t think the pandemic is “over” and always expected cases to rise this summer upon reopening.

      I am opposed to remote learning and lockdowns, think masks have utility in some situations, and mainly believe people should be wary of potential super-spreader events.

      I support any vaccine mandate or passport requirement that can be implemented. I have absolutely no libertarian philosophical opposition to any of that. My strong pro-vax position leads me to dislike the same restrictions being imposed upon those vaxed and those not.

      I give myself a B-minus / C-plus.Report

      • InMD in reply to PD Shaw says:

        Do you think this routine convinces anyone? It isn’t principle, it’s narcissism and the attitude is why we’re still in this mess.Report

      • Philip H in reply to PD Shaw says:

        We don’t trust people with their own health. They are being told by surgeon generals in two administrations, the nation’s top infectious disease experts, state health officers, and their own doctors to mask up and get vaccinated, and they are instead running around yelling “YOU CAN”T MAKE ME” – right up until they get intubated because their lungs are shutting down. And along the way they are infecting and endangering untold numbers of their family members and neighbors.Report

        • Philip H in reply to Philip H says:

          People won’t stay home unless the government forces them to. And death rates among vaccinated people are nowhere near death rates of unvaccinated people. Hospitalization rates of vaccinated people are nowhere near hospitalization rates of unvaccinated people. the non-sterilizing vaccine is working.

          And masks – worn correctly so as to cover nose and mouth – are effective at preventing an infected person from transmitting disease through exhalations.

          People are still, however, largely not making good sound risk averse choices. Many because they don’t know how; others because they believe doing so means they will no longer be in their preferred in group.

          I get that you don’t see masking or this vaccine as Gold standard care. As was already pointed out, most vaccines in use today aren’t at your gold standard but are highly effective. Which tells me the Bronze standard care we do have in place – when used properly – will buy us time to get an even better handle on this.

          But again – people are not taking even the bronze standard for a variety of mostly bad reasons. They can’t be trusted to “do the right thing” no matter how much you or I or anyone else wants them to.Report

    • InMD in reply to Jaybird says:

      Count me as group C. I’m vaccinated and in a county where allegedly 80% have had at least one shot. All these boobs out in Arkansas and Missouri? Well that don’t confront me. And I see no reason to get in with the ongoing performances suggesting it should.Report

      • North in reply to InMD says:

        I confess in my darker moments I channel Kirk from Star Trek VI when it comes to the willfully unvaccinated* :
        https://tenor.com/view/let-them-die-star-trek-gif-10833966

        *exempting those who, for various medical reasons, can’t be vaccinated safely.Report

        • InMD in reply to North says:

          Yea I talk a big game but I’d wear a mask in a hospital or nursing home. I think the rest of this is self correcting. We’ll be at over 200 million vaccinated in the next few weeks. No need to back track in places with high rates of vaccinated people. And places without? Well they’ll figure it out soon enough.Report

          • North in reply to InMD says:

            As me mum likes to say “You can either learn or feel.”Report

          • InMD in reply to InMD says:

            Will I really have to? Because the government doing irrational things in contravention of empirical evidence is completely consistent with my priors. The belief that this can and will happen may in fact be the biggest and most foundational prior I’ve got.Report

          • Philip H in reply to InMD says:

            And places without? Well they’ll figure it out soon enough.

            Living in one of those places – no they won’t. Two weeks ish ago the governor of Alabama admitted publicly that this is now a pandemic of the unvaccinated and expressed what appeared to be genuine surprise that so few people were getting vaccinated, social distancing and wearing masks. But she change NOTHING in state level policy or executive orders.

            Our governor in Mississippi steadfastly refuses to consider mask mandates or vaccine mandates – though thankfully the school districts around us have mostly masked up as school is starting. He won’t lockdown the state again no matter who begs him too.

            And Florida’s Governor seems to take a point of pride in rigging the system to kill the maximum number of Floridians possible, while also rigging the counting system to try and mask said death. He does so because he believes it’s how he gets elected President if Trump doesn’t run.

            Louisiana’s moderate governor may go a few steps back down the road, but even the arrival of federal Disaster Medical Teams in Baton Rouge has yet to move him.

            There will be no national lockdown, and not likely any lockdown or mandates in the red portion of America, no matter how much death it brings.Report

            • InMD in reply to Philip H says:

              I don’t think there will be lockdowns or new mandates either. I think the fear and chaos will drive vaccination until it passes whatever threshold it takes to calm things down. There have been news stories in the last ~week or two saying the rate is finally increasing again, particularly in those places where it is low. Sadly far more people will die then really need to but I see no solution other than to let it play out.Report

              • Philip H in reply to InMD says:

                We don’t have the same form of government. It would have to be state by state, and the red states are not going to shut down even in the face of massive death.Report

    • Mike Schilling in reply to Jaybird says:

      I’m group F for Florida Man. The unvaccinated represent a threat of grievous bodily harm*, and Stand Your Ground should apply.

      * In several ways:
      1. They’re virus factories, and vaccination is not 100% effective.
      2.The more infected, the higher the chances of a really nasty mutation.
      3. They’re taking ICU beds away from people with less avoidable problems.Report

      • Jaybird in reply to Mike Schilling says:

        At the beginning of the summer, I was a huge fan of using the carrot.

        Now at the end of the summer, I’m fine with the stick. I saw this today and it struck me as a good policy:

        Now it does seem to be gameable (just borrow a friend’s positive test and get two weeks off!) but, assuming that someone won’t do that, it seems like a good nudging policy.Report

        • Mike Schilling in reply to Jaybird says:

          “Man, I had a bad cold. Two weeks in the ICU!”Report

        • Marchmaine in reply to Jaybird says:

          Eh, I don’t think that’s particularly good policy… it’s disproportionate. Better would be:

          1. If you’re sick and vaccinated we’ll pay you sick leave… as long as it takes.
          2. If not vaccinated, no pay… (other than whatever the current policy is for sick-days that your lawyers will tell you you have to do anyway).

          Plus, you won’t be setting yourself up for the inevitable stupidity of re-hiring certain ‘important’ people after you’ve (symbolically) fired them… or not actually firing some of those people in the first place…

          It would be even better policy if Lowes brought people into their warehouses/stores to vaccinate folks where they work… giving them a bonus for getting it, and giving them the next day off with pay. Which, by the way, is how my son was vaccinated by Amazon at the warehouse job he was working.Report

          • Philip H in reply to Marchmaine says:

            It may not be good policy, but with the existence of Long Covid and the potential for lawsuits about unsafe workplaces (plus the drain on profits that sick leave undoubtedly represents to a great many bean counters), its probably seen as great fiduciary decision since corporations are ALL ABOUT short term profit maximization these days.Report

            • Marchmaine in reply to Philip H says:

              Yes and No… sure, anyone can sue for any reason… but absent an actual Vaccine mandate, if their concern was lawsuits, they’d follow the maximal public guidance which would be for masking indoors. Or, if it’s truly a fear of hypothetical future lawsuits then they would be compelled to fire the unvaccinated *before* they get sick because that’s literally how the virus spreads. Firing people after they got sick doesn’t slow the spread (hence, unsafe working conditions) and is simultaneously punitive… and likely will hit a lot of people that team good thinks shouldn’t be hit disproportionately.

              Lowes is attempting to drive policy beyond corporate CYA, and… I’ll put a marker down that they will fail and/or retreat when they realize that their policy disproportionately targets POC who are proportionally less vaccinated… not to mention the inevitability that they won’t fire ‘someone’ who they need or want to keep. It’s posturing getting ahead of good policy. It happens a lot.

              And that’s assuming the tweet is even truly Lowes’ policy… which it might not be.

              The large chain one of my daughters works at is taking the CYA approach… shoppers don’t have to mask, but employees do. That’s pure CYA.Report

      • Dark Matter in reply to Mike Schilling says:

        Add huge amounts of economic damage and disruption to that list. The virus doesn’t have to exist any more, they’re insisting that it must.Report

      • InMD in reply to Mike Schilling says:

        If we had those little like buttons I would click it immediately for this comment.Report

  9. Jabberwocky says:

    Most of the people in Israel that are in serious condition are vaccinated:
    https://www.jpost.com/israel-news/coronavirus-who-are-the-serious-patients-in-israel-675924
    This is mostly the case with the over60 contingent, but for those who are saying that the vaccines prevent serious COVID19, this is a challenge to that statement.Report

    • Philip H in reply to Jabberwocky says:

      153 over age 60 fully vaccinated out of 250? In a fully vaccinated population of 5.39 Million? 0.003% of the vaccinated population is people over 60 with serious COVID? Color me unimpressed statistically.Report

    • Brandon Berg in reply to Jabberwocky says:

      The key question to ask here is what percentage of people over age 60 are vaccinated. If it’s significantly more than 73%, then the vaccine is likely to be very effective against serious disease. If 2% of the population is unvaccinated and that group is 27% of serious cases, that’s pretty good.

      Here are the most recent data I could find:

      https://eu.boell.org/en/2021/06/14/access-covid-19-vaccine-israel

      60-69 at 86.6%, and the older groups at 93-95%.

      It’s hard to get a good idea of the effectiveness without a more detailed breakdown of serious infections among vaccinated individuals by age. I would guess that they’re clustered towards the high end.

      It’s important to remember that we can’t expect magic. Some people, especially the elderly, have weak immune systems that don’t respond to vaccination as well as we might like. Plus the vaccines aren’t targeted to the currently dominant strain. They give your immune system a big head start, but it has to do the rest of the work, and it has to do it fast enough to keep the viral load from getting out of control.

      And no, the issue isn’t that it’s a non-sterilizing vaccine. The delta lineage was already starting to spread by the time the vaccines were approved, and it’s had no trouble spreading in countries with low vaccination rates. It was selected to spread better among unvaccinated populations; vaccine escape was a spandrel.

      Anyway, the vaccine does protect against serious illness even from the delta lineage, just not perfectly.

      Probably the best solution going forward is a) to keep up moderate NPIs, b) ramp up vaccine production to get the world vaccinated, and c) roll out boosters targeted to one or more variants of concern.

      In the meantime, you should probably patent your design for a sterilizing vaccine. You’re sitting on a gold mine.Report

  10. Jaybird says:

    Astral Codex Ten remains worth visiting. I got the email earlier discussing the comments from Acemoglu And AI and Scott discusses something I did not know:

    One of the main problems AI researchers are concerned about is (essentially) debugging something that’s fighting back and trying to hide its bugs / stay buggy. Even existing AIs already do this occasionally – Victoria Krakovna’s list of AI specification gaming examples describes an AI that learned to recognize when it was in a testing environment, stayed on its best behavior in the sandbox, and then went back to being buggy once you started trying to use it for real. This isn’t a hypothetical example – it’s something that really happened. But it happened in a lab that was poking and prodding at toy AIs. In that context it’s cute and you get a neat paper out of it. It’s less fun when you’re talking twenty years from now and the AI involved is as smart as you are and handling some sort of weaponry system (or even if it’s making parole decisions!)

    Holy crap.

    That indicates “theory of mind”.Report

  11. PHilip H says:

    I’m vaccinated. I mask up. I wash my hands. I social distance and I’m working from the same desk at my house I have been since March 2020. I’ve done everything I can to stay safe. So when my family needs to eat, I go out, I’m as quick as I possibly can be, and I go at off peak hours.

    Because I care about my fellow man too.Report