Covid in India Approaching Worst Case Scenario

Andrew Donaldson

Born and raised in West Virginia, Andrew has been the Managing Editor of Ordinary Times since 2018, is a widely published opinion writer, and appears in media, radio, and occasionally as a talking head on TV. He can usually be found misspelling/misusing words on Twitter@four4thefire. Andrew is the host of Heard Tell podcast. Subscribe to Andrew'sHeard Tell Substack for free here:

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7 Responses

  1. North says:

    This is nightmarish. Setting aside the pure human toll of this mess; this roiling mass of infections with the vaccines now being sprayed into it strikes me as absolutely terrifying. I’m no expert in medical science but isn’t this close to the definition of an environment where a vaccine busting variant of Covid could have the maximal odds of emerging? Jesus agnostic Christ!Report

    • JS in reply to North says:

      I don’t think viruses react to vaccines quite like they do antibiotics. The human immune system is pretty good at “Hey, that looks suspiciously like something I’ve seen before”, and since we’re targeting the spike protein that allows for infection in the first place (so that significant changes to avoid immune response are likely to maladapt for infection)….

      It’s more “eroding vaccine efficacy” rather than suddenly seeing strains that laugh at your immune response — that is, you’d see vaccinated folks more and more likely to get a mild case of COVID-19, rather than have outright immunity, as their immune systems already have a leg up.

      As such, you’d want to retune the vaccine to the dominant strains — similar to yearly flu vaccines, but mRNA, to get more outright immunity and less mild cases. Given the vaccine options we have now and the wealth of research data, updating at least the mRNA ones should be fairly easy to test and push through.

      It’s certainly not optimal, of course. Killing this off like polio would be optimal. I don’t think that was ever in the cards for COVID-19. Of course having a raging outbreak with only a portion of the population infected is probably as worst case as you can get if you HAVE a vaccine.

      I just don’t think immune systems and vaccines are directly comparable to antibiotics and bacteria in terms of exactly how they “resist” each other.Report

      • North in reply to JS says:

        I earnestly hope you are right but, like you said, this is the worse case scenario either way. I don’t want our current stable of vaccines to be shot willy nilly into a raging pandemic inferno. I want them overwhelmingly deployed to summarily crush or forestall pandemics.Report

  2. Pinky says:

    India’s covid fatalities per million people is about 10% of the hardest-hit countries. Still, the completely “unbent” exponential curve in the current data (both new cases and deaths) and the very low percentage of the population vaccinated are worrying. Guu is right that the worst-case scenario with a virus that kills 1% of its victims is only a 1% death toll, but still it’s got the makings of a tragedy.Report

    • Blomster in reply to Pinky says:

      As I understand it, it is 1% under the assumption that the population has access to hospital care. If they do not, it turns into 4%. It seems India is at a point where their hospitals are so overburdened their death rate is going to climb to that 4%.

      Absolutely horrific.Report

      • JS in reply to Blomster says:

        4% is actually low-balling it, as an overloaded healthcare system can’t handle regular healthcare problems, so you start seeing excess deaths from other causes as well.Report

      • Pinky in reply to Blomster says:

        I was addressing the concerns of a comment that’s since disappeared.

        There are a lot of factors. A younger, less-obese population with less access to health care across some of the world’s extremes of high and low population density? Any non-expert is only guessing. The fatality rate will be closer to 1% than 70%, but even so, 1% of India is an enormous number.Report